Asymmetric Catalytic Aziridination of Cyclic Enones <<>>
Written by Francesco De Vincentiis, Giorgio Bencivenni, Fabio Pesciaioli, Andrea Mazzanti, Giuseppe Bartoli, Patrizia Galzerano, Paolo Melchiorre on May 28, 2010 – 1:16 am -The head catalytic method for the asymmetric aziridination of cyclic enones is described. The presented organocatalytic scenario is based on the use of an easily nearby organocatalyst that is proficient to transmute a broad extend of cyclic enones into the desired aziridines with extremely lofty enantiomeric chastity and wares chemical yield. Such a method may really soundly begin up new opportunities to stereoselectively equip complex chiral molecules that secure an indane moiety, a framework that is inaugurate in a large slew of bioactive and pharmaceutically important molecules <<>>
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